GONORRHEA
Definition
• All diseases caused by Neisseria gonorrhoeae, a gram negative
diplokokus
• Generally about :
• All diseases caused by Neisseria gonorrhoeae, a gram negative
diplokokus
• Generally about :
-
Urethral
-
Endocervical
-
Rectum
-
Pharyngeal
-
Conjunctiva
• hematogenous spread:
DIG (Disseminated Gonococcal Infection)
Gonorrhea Attack
• Men
- Urethra
- Ex tyson
- Ex Cowper
- Ex parauretra
- Prostate
- The epididymis
- Testis
- Conyunctiva
- Larinks
- Pharinks
- rectum
• Women
- cervix
- Bartholin
- Ex skein
- Salphinx
- Ovary
- Pid
- Joints
- Septicemia
- Pericard
- disseminated
Etiology
• Gram negative
• Intracellular
• Diplokokus
• hematogenous spread:
DIG (Disseminated Gonococcal Infection)
Gonorrhea Attack
• Men
- Urethra
- Ex tyson
- Ex Cowper
- Ex parauretra
- Prostate
- The epididymis
- Testis
- Conyunctiva
- Larinks
- Pharinks
- rectum
• Women
- cervix
- Bartholin
- Ex skein
- Salphinx
- Ovary
- Pid
- Joints
- Septicemia
- Pericard
- disseminated
Etiology
• Gram negative
• Intracellular
• Diplokokus
Epidemiology
• 350 million people are infected each year
• Gonorrhea 60%
• Infection mixture
• Developed countries Chlamydia> Gonorrhea
• Cofaktor HIV / AIDS.
• The received treatment and recovered about 10%
Pathogenesis
• Adhesions (pili and surface proteins)
• Epithelial cells penetrate the network.
• Pmnl
• Micro abscess
• Deployment
Clinical
• incubation 2-5 day
Clinical Symptoms :
Infection in men
• anterior urethra
- Test thompson
• Complaints disuri, urethral discharge
• Mucus turbidity until pus
Examination
• Mue: edema, erythema, ectropion, purulent discharge
Infection in women
60-80% asymptomatic.
Complaint :
• vaginaldischarge
• Disuri
• intermenstrual bleeding
• Menorrhagia
• Back pain
Diagnosis
• Anamnesis, clinical, laboratory
• Laboratory
- Cat Gram duh body
- Culture: Thayer martin / modifications TM
- Definitive test (test oxidase, Fermentase)
- Test NGPP (Beta Lactamase, Yodometri, Penicillin disk Difusion, Thomson Tests
- Elisa
Men : materials from the body duh urethra / sed.urine / massage prostate secretions
Women : material from the urethra, srviks, estuaries kel.bartholin, rectum
• 350 million people are infected each year
• Gonorrhea 60%
• Infection mixture
• Developed countries Chlamydia> Gonorrhea
• Cofaktor HIV / AIDS.
• The received treatment and recovered about 10%
Pathogenesis
• Adhesions (pili and surface proteins)
• Epithelial cells penetrate the network.
• Pmnl
• Micro abscess
• Deployment
Clinical
• incubation 2-5 day
Clinical Symptoms :
Infection in men
• anterior urethra
- Test thompson
• Complaints disuri, urethral discharge
• Mucus turbidity until pus
Examination
• Mue: edema, erythema, ectropion, purulent discharge
Infection in women
60-80% asymptomatic.
Complaint :
• vaginaldischarge
• Disuri
• intermenstrual bleeding
• Menorrhagia
• Back pain
Diagnosis
• Anamnesis, clinical, laboratory
• Laboratory
- Cat Gram duh body
- Culture: Thayer martin / modifications TM
- Definitive test (test oxidase, Fermentase)
- Test NGPP (Beta Lactamase, Yodometri, Penicillin disk Difusion, Thomson Tests
- Elisa
Men : materials from the body duh urethra / sed.urine / massage prostate secretions
Women : material from the urethra, srviks, estuaries kel.bartholin, rectum
Men
• Tisonitis
• Parauretritis
• Cowperitis: pain in the perineum, disuri
• Infection post urethra → vesica urinaria : polakisuri, hematuri
• prostatitis : pain in the perineum, feels pain when defecating, febrile
• Vesikulitis
• Funikulitis
• Epididymitis: febrile, edema, scrotal skin inflammatory signs (+)
• Infertility
Women
• Bartholinitis: labium Mayus edema (tu. third bottom),
signs of acute inflammation
• PRP → scarring, tubal → infertility
• salpingitis
• Disseminated: Arthritis, myocarditis, endocarditis, pericarditis,
meningitis and dermatitis
Therapy
Consider, effectiveness, single dose, side effects, site of infection, resistance, the possibility of infection of C. trachomatis simultaneously
Anogenital Infection, Complications (-)
First-Line
Cefixime 400 mg/single dose oral
Second-Line
Ciprofloxacin* 500mg/oral single dose
Ofloxacin* 400mg/oral single dose
Spektinomisin 2g single dose intra-muscular
*) Is not recommended in children / adolescents
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