Tuesday, June 4, 2013

PEDIATRIC INFECTIOUS DISEASES

PEDIATRIC INFECTIOUS DISEASES

Infection is the attempt of the organism to survive
    - Viruses without cytoplasm, to enter into another cell
    - Germs get into the organ
    - Parasites (worms) in the gut/blood
The victory is temporary: the change is eternal: adaptation and mutation, addition and dilesi
supporting climate all year
Eradication of mosquitoes is against nature

The pyramid of infection and prevention of sickness

ENVIRONMENT

Environment of the tropical belt that is full of strife,
Lean food, either protein or carbohydrates


Population Density And Pressure Environment
"rapid population growth and highly oriented natural resources, causing a change in the balance of the world and chemically biologik"

Violation of rules of sanitary hygiene & health
Unbridled Urbanization
   – transfer of (displaced) population is a result of catastrophic speed
   – Causing the density and density and trigger shortages of housing, water, sewage effluents
Causing transmission of disease more quickly

GERMS
Germs cause infection must have the ability to:
Do the invasion
Multiplication
Transmission to other individuals
Germs in design to stay in extrem conditions, are able to live
   - to 10,000 m in the ground
   - Several thousand feet of aerial
   - Under the volcano
   - In the dust the spores and symptoms Cl.
There are cells in the human body prokaryotik 10 more than eukaryotik cells

HOST-THE HOST
healthy and strong is not enough
Baby blm developed immune system
Children become sick ok:
   - virus/germs enter the body
   - environmental influences (transmission/pollution)
   - are not immune to infectious disease
Movement of anti-immunisation
 

THE PATHOGENESIS OF INFECTION
  • Bondingandthe entry ofgerms
  • Invasion ofgerms,germcells,phagocytesand replies
  • The spread ofgerms
  • The immune responseto infection
  • Strategiesto facegermimmune response
  • The mechanism ofcell damage
  • Healinginfections
  • Failureof eliminationgerm
  • factorsaffectinggerms andhostvulnerability
DISTRIBUTION/TRANSMISSION OF GERMS
Horizontal,
through the air, water, food, vector
Vertical,
mother to baby through the placenta, in breast milk
THE PROCESS OF INCLUSION (INVASION) GERM
  1. Attaches to epithelium, eyes, sores etc
  2. Stick on parts exposed
  3. Stick to the specific receptor (trophisme)
  4. Piercing, damage the skin, epithelial
  5. Cause inflammation
  6. Direct entry
COLONIZATION AFTER ADHESION:
• Growing in epithelial cells
• Food for germs:
   - Iron
   - Tryptophan
• Invasion of the subepitel
   - Pass membrane basal
   - 3 types of body defense Intercepted: liquid cell tissue, lymph, phagocytes
• Intracellular Germ
   - To spread throughout the body. sign in blood pb as the germs in the blood cell mobile
   - Not able to target organs replicasi, could be dormant

THE GROWTH OF GERMS IN THE EPITHELIUM
  1. Viral infections respiratoir,
  2. Biofilm, EFL (epithelial lining fluid)
  3. Viral invasion does not occur to the underlying tissue,
  4. Factor nonimunologi (innate immunity/physical barrier)
  5. Infection stop
 INVASION OF SUB-EPITHELIAL
  • Results from the EFL or damaged epithelial cells
  • Invasion into
  • Basal epithelial membrane being held as a filter
  • Membrane damage due to inflammatory & cell damage
  • Germ held the invasion of sub-epithelial tissue

IN SUB-EPITELKUMAN FACE 3 SYSTEM
1. Fluid Network
  • Plasma protein including imunoglobulin
  • A media culture germs
  • Germ multiplication, encourage a variety of inflammatory response products, ignite
  • There are many more, complement, other serum factor (is antikuman)
  • Contain anti germ of platelets, macrophages, a
2. the Lymph System
3. Cells Phagocytes

Pictures
Phagocytosis, macrophages inside the phagolysosome & Endocytosis

THE SPREAD OF GERMS
1. Enter lymph lymph channels-ex.
2. kel lymph:
    - filter
    - the process of the immune system work
3. not being able to stop him, thus spreading
4. Enter the blood vessels of lymph channels lewt
5. Removing material, dissemination of

HEALING INFECTIONS
Multiplication of germs in the stop
1. germs don't spread
2. the amount of germs is reduced
3. the germs off. Next:
Spruce up the network breaks down
• clean the rest of the germs
• spruce up
• reconstruction
• cured

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